Riot police were brought to control crowds inside and around the Toumba stadium for Sunday's table-topping clash between rivals PAOK and Olympiakos.
Some supporters also jumped the turnstiles, with large numbers of fans forced to wait outside the ground.
PAOK moved a step closer to winning their first title in 34 years, and also finishing the league unbeaten, with a 3-1 win over Olympiakos.
The Thessaloniki side took an early lead, with Adelo Vieirinha and Diego Bisewar scoring in the first 20 minutes. Chuba Akpom added a third before Daniel Podence's consolation three minutes from time.
Last season's clash was marred by clashes and controversy after PAOK's owner Ivan Savvidis invaded the pitch with a gun. The Greek Superleague was temporarily suspended and faced warnings from European football's governing body UEFA.