There are approximately 5,000 hotels and overnight accommodations in the Florida Keys.
Almost all of them have agreed to close for two weeks beginning Sunday, March 22.
This is to curb the spread of the coronavirus, reports Business Insider.
Visitors currently staying in the Keys will have until 6 p.m. on March 22 to evacuate.
The announcement comes on the heels of other closures in the Keys.
This includes tourist hotspots as well as theaters and museums.
Closures across Florida meant to enforce social distancing haven't stopped spring breakers from flocking to beaches in full force.