Washington (dpa) - Presumptive Republican presidential nominee Donald Trump blasted Democratic opponent Hillary Clinton on Wednesday as a "world-class liar" who is beholden to special interests and personally benefited from her political connections.

"She gets rich making you poor," Trump said in a speech in New York, outlining his attacks against Clinton as the candidates shift their attention from the long primary season to the November general election.

He pointed to contributions to the Clinton Foundation, run by her husband, former president Bill Clinton, from foreign entities and charged she had used the State Department as a "personal hedge fund." He targeted paid speeches she delivered to investment banks since leaving office, but has so far refused to make public.

"Hillary Clinton may be the most corrupt person ever to seek the presidency," Trump said.

His attacks on her corporate connections echoed concerns raised by Clinton's Democratic primary challenger, Bernie Sanders, and Trump called for Sanders' supporters to join his campaign rather than back Clinton.

The remarks came one day after Clinton delivered a speech arguing that Trump would be dangerous for the US economy. Trump has faced ongoing questions about his candidacy in recent weeks amid a series of inflammatory statements, this week's sacking of his campaign manager and the release of financial statements showing Trump significantly lags Clinton in fundraising.

Trump took aim at Clinton for support of trade deals, including the North American Free Trade Agreement, which was passed during Bill Clinton's presidency, and the Trans Pacific Partnership (TPP) agreed by 12 countries last year.

Although Clinton has distanced herself from the TPP, Trump said she would adopt it, costing millions of US jobs.

He lambasted her tenure as secretary of state, charging that Clinton had "almost single-handedly" destabilized the entire Middle East. He pointed to her support as senator for the 2003 invasion of Iraq and advocacy as secretary of state for the international air campaign in Libya as well as the attack by militants on the US consulate in Benghazi that left four US citizens dead.

"In short, Hillary Clinton's tryout for the presidency has produced one deadly foreign policy disaster after another," Trump said.

Trump, who has called for a ban on Muslim immigration into the United States and vowed to build a wall on the US-Mexican border to keep out illegal immigrants, charged that Clinton wanted to drastically increase the acceptance of Syrian refugees, endangering national security.

"She lacks the temperament, the judgement and the competence to lead our country. She should not be president under any circumstances," he said, in remarks that echoed Clinton's own criticism of Trump.

Clinton's campaign dismissed Trump's remarks as a "distraction" that offered "more hypocritical lies and nutty conspiracy theories."

"Donald Trump continues to prove that he is unqualified and unfit to be president," spokesman Glen Caplin said.

Trump claimed he was the only candidate who could revive the US economy, create jobs and fix crumbling infrastructure.

He said he would devote the first 100 days of his presidency to changing immigration rules, standing up to countries that cheat on trade, changing regulations that favour US companies moving abroad, and instituting tax reform, among other promises.

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