Four soldiers were killed and two were injured in a roadside bombing in Mardin province that's being blamed on the Kurdistan Workers' Party (PKK), Dogan news agency reported Friday.
Turkey had earlier launched airstrikes against alleged PKK targets in the south-eastern province of Diyarbakir, Dogan reported.
The report said multiple F-16s were used the previous day in the strikes in Silvan district.
Turkey has increasingly been using heavy weapons in the mostly Kurdish south east, causing considerable damage to property.
A ceasefire between the state and the PKK broke down in July amid mutual recriminations after peace talks stagnated.
Fighting in the latest round of violence has been characterized by intense urban battles involving Kurdish youth militias and Turkish forces.
Many hundreds of people, including civilians, have been killed while hundreds of thousands have been displaced.
Turkish officials have ruled out fresh talks with the PKK.