Two people were killed and 20 injured Wednesday in a car bombing in a town near the Syrian border in south-east Turkey, broadcaster CNN Turk reported.
The bomb went off near a police headquarters in Midyat district of Mardin province. Images showed heavy damage to a building, whose front was blown out, and smoke rising from the location where the explosion took place.
The blast comes a day after a car bombing in Istanbul which targeted security forces and killed 11 people, including six members of the police.
Mardin has seen a series of curfews imposed on towns and districts since last year, during fighting between state security forces and Kurdish fighters, mostly from the Kurdistan Workers' Party (PKK).
Security forces recently announced that operations in Nusaybin, one of the areas of Mardin seeing the most intense conflict, ended over the weekend, after nearly three months.
A ceasefire and peace process collapsed in July, leading to renewed fighting in a war ongoing for more than 30 years and killing more than 40,000 people. Turkey's government has ruled out a return to peace talks with the PKK, which it views as a terrorist group.
The new round of violence, which is largely focused on the mostly Kurdish south-east, has claimed many hundreds of lives, though some estimates say thousands have been killed.
Many Kurds in Turkey's south-east complain of systemic discrimination by the state, with demands for greater rights and autonomy.
Turkey is also using its air force in the conflict, launching strikes against alleged PKK targets inside the country and in northern Iraq.