A former correspondent for Fox News was on Monday named the next spokesman for the Vatican, while his deputy will - for the first time - be a woman.
Greg Burke, 56, will replace Federico Lombardi, 73, who has held the post for a decade.
Spanish journalist Paloma Garcia Ovejero, 40, will be the first woman deputy of the press office.
The appointments are part of a broader restructuring and modernization of the Vatican's media department.
The two will take on their new roles from August 1.
Lombardi was appointed as head of the Vatican press office by Pope Benedict in 2006.
Burke earlier worked as a communications strategist for the Vatican in 2012. He is a member of the conservative Opus Dei movement.
Since 2012, Ovejero was the Rome and Vatican correspondent for numerous media, Vatican Radio reported, adding that she speaks Spanish, English, Italian and Chinese.
Pope Francis has been quick to embrace social media, and has millions of followers. The @Pontifex handle on Twitter is available in English, Spanish, Italian, Portuguese, French, German, Polish, Latin and Arabic.
In March, the pontifex joined photo-sharing app Instagram under the name @Franciscus, Latin for Francis.
The first photograph uploaded on Instagram was of Francis praying, the image accompanied by the words "pray for me," in nine languages.